On February 7, 1862, the Stars and Stripes took part in the attack on Roanoke Island, N.C. On February 20, while transferring ammunition to Isaac N. Seymour, that ship struck the submerged anchor of the USS Louisiana and sank. Most of the crew were saved by the Stars and Stripes.
The ship operated in North Carolina waters and helped capture New Bern in mid-March.
It returned to Norfolk on 4 June for badly needed repairs and six days later returned to blockade duty off North Carolina.
Shortly before dawn June 27, 1862, the Stars and Stripes helped the USS Cambridge destroy the blockade runner Modern Greece near the Cape Fear River off Fort Fisher. (I wrote about this on June 27 only it did not mention the USS Stars and Stripes being involved, just the USS Cambridge.)