Since I had never heard of the USS Santee, I had to inquire further into its history.
It was a three-masted, wooden hulled sailing frigate. and one of the last sailing frigates in active service. In the Civil War it was crewed by 480 and fitted out with an array of heavy guns.
It did blockade duty and later served as a training ship for the USNA.
It was rated for 44 guns and construction on the Santee began at Portsmouth Navy Yard in 1820, but lack of funds lef to it not being launched until 16 February 1855, but was not commissioned until 9 June 1861, with Captain Henry Eagle in command.